Research Project

Kids-CT

Multimodal imaging for a modular CT device for diagnostics in children.

Diagnostics and treatment planning often draw on a range of imaging modalities – CT, ultrasound, photographic and 3D cameras, endoscopy. Bringing these together spatially is one of the most complex tasks in medical image processing. Kids-CT pursues the vision of a modular, open scanner system with freely interchangeable sensor modules. Within this project, Dornheim researched multimodal imaging: hardware-based 3D registration, visualization, and processing of the image data – with the goal of increasing the information content while reducing the radiation dose.

Kids-CT – 3D visualization of a modular CT examination room with a time-of-flight camera for the spatial localization of the sensor modules
Multimodal imaging for a modular CT system Subproject: multimodality with hardware-based 3D registration Duration: 10/2017 – 03/2021 © Photo: Dornheim Medical Images

in collaboration with partners from science and industry in Magdeburg

A modular, open CT system with freely interchangeable sensor modules

Commercially available CT scanners offer little scope for adding extra components or connecting custom sensors – which significantly hampers the corresponding research and development efforts. The overall Kids-CT project therefore pursued the vision of a unique, modular medical scanner system distinguished by a variety of freely interchangeable sensor modules for image acquisition – with a CT device as the base module and open hardware and software interfaces.

The subproject carried out by Dornheim focused on multimodality: the goal of deriving a higher information content from spatially localized medical images (CT, ultrasound, photographs, and others) for diagnosis and treatment. In addition, the scanning process and image reconstruction can be optimized in a targeted manner to further minimize radiation and examination time – a decisive advantage, especially in children.

Multimodality and spatial localization

To combine the various acquisitions without permanently fixing the sensors to the CT device, the approach relies on an optical tracking system: marker-based detection is used to track the 3D position and orientation of the sensor modules and the patient. A time-of-flight camera installed above the CT table forms the center of the coordinate system, into which further – including freely movable – devices are transformed. In addition, QR codes and, above all, Bluetooth beacons proved effective in reliably detecting and identifying devices in the examination room even when they are optically obscured.

A web-based, adaptive user interface was developed for controlling and integrating the sensors. A configuration file automatically embeds a device's available parameters into the web interface; a template function allows preconfiguration by administrative users. Technically, the concept builds on open standards (ROS) and a containerized infrastructure (Docker), in which the web interface and device connection communicate bidirectionally via the WebSocket protocol – so the system can be flexibly transferred to other devices and interfaces.

Use case: wound care

Wound care was chosen as an exemplary use case – a complex field shaped by intersectoral and interdisciplinary work in which a wide variety of imaging devices is used. New mobile devices with integrated 3D camera technology (iPhone Pro, iPad Pro) opened up the possibility of capturing 3D scans, for example of wounds, directly with a handheld device. In prototype apps, interaction concepts for touch interfaces were developed that allow structures to be marked and their areas and dimensions to be calculated to scale – helpful for treatment and documentation.

Beyond this, mobile, Wi-Fi-enabled ultrasound probes and a hyperspectral camera were integrated, and their acquisitions were fused with 3D scans. Through the cloud-based system, multiple users can view and discuss the results together across locations – an important building block for telemedical and interdisciplinary collaboration.

Contributions by Dornheim Medical Images

Building on the Dornheim Segmenter®, matured over many years, Dornheim brought its expertise in image analysis, 3D reconstruction, and visualization to the collaborative project. Among other things, methods were developed for the spatial localization and calibration of the sensor modules, for 3D surface reconstruction, for the multimodal visualization of overlaid volume data, as well as cloud concepts for compute-intensive image processing and centralized data management. The subproject was successfully completed from both a scientific and a technical standpoint.

Insights into the project

Concept of a holistic system with the Dornheim.Cloud as a central, cross-location interface for various sensor modules
Holistic system with the Dornheim.Cloud as a central interface for various sensor modules.
Software assistant for the calibration and spatial localization of the external modalities via the tracking system
Assistant for the calibration and spatial localization of the sensor modules via the tracking system.
Clinical test acquisitions: fusion of a hyperspectral camera and a 3D scan from a time-of-flight camera
Clinical test acquisitions: fusion of a hyperspectral camera and a 3D scan (time-of-flight camera).

Scientific publications

The results achieved in the project were presented together with the project partners at status meetings as well as at STIMULATE sessions. Selected topics of the subproject were also written up in the form of a bachelor's thesis.

What emerged from the project

From the research results, Dornheim further developed several exploitable building blocks: a 3D scanner app with an accompanying acquisition adapter for iPhone and iPad, including measurement functions for image evaluation; an app for visualizing medical image data; and corresponding specialized modules for the Dornheim.Cloud. The result is a holistically supportive system of interacting components – from image acquisition through localization and multimodal visualization to documentation. The market proved particularly attractive for wound care and aesthetic surgery; on this basis, pilot projects were prepared.

Bundesministerium für Bildung und Forschung (BMBF)

Bundesministerium für Bildung und Forschung (BMBF)

The project "Modular CT device for diagnostics in children (Kids-CT)" was funded by the BMBF under the German federal government's Health Research framework program. Dornheim carried out the subproject "Multimodal imaging with a hardware-based approach to the 3D registration, visualization, and processing of clinical image data from freely interchangeable image sensor modules" (funding reference: 13GW0229B).